Publications

Mapping Nanoscale Forces and Potentials in Live Cells with Microsecond 3D Single-Particle Tracking

Shangguo Hou^†, Chen Zhang^†, Anastasia Niver and Kevin D. Welsher

Chemical & Biomedical Imaging, 2026

url pdfdoi: 10.1021/cbmi.5c00293

Review of Machine Learning for Single-Particle Tracking: Methods, Challenges, and Biophysical Insights

Chen Zhang^†, Ran Liu^†, Zichen Ding, Peng Lu, Weiming Tian, Yan Zhao, Jiaye He and Shangguo Hou

Chemical & Biomedical Imaging, 2025

url pdfdoi: 10.1021/cbmi.5c00146

Hour-Long, Kilohertz Sampling Rate Three-Dimensional Single-Virus Tracking in Live Cells Enabled by StayGold Fluorescent Protein Fusions

Yuxin Lin, Jack Exell, Haoting Lin, Chen Zhang and Kevin D. Welsher

The Journal of Physical Chemistry B, 2024

urldoi: 10.1021/acs.jpcb.4c01710

Active-Feedback 3D Single-Molecule Tracking Using a Fast-Responding Galvo Scanning Mirror

Xiaochen Tan, Shangguo Hou, Anastasia Niver, Chen Zhang, Alexis Johnson and Kevin D. Welsher

The Journal of Physical Chemistry A, 2023

urldoi: 10.1021/acs.jpca.3c02090

Information-Efficient, Off-Center Sampling Results in Improved Precision in 3D Single-Particle Tracking Microscopy

Chen Zhang and Kevin Welsher

Entropy, 2021

url pdfdoi: 10.3390/e23050498